Mendelsohn et al.’s study is important because it demonstrates that hypnotic suggestions influence brain activity, not just behavior and experience. Hypnotic effects are real! This fact has been demonstrated clearly in earlier work, for instance, by psychologist David Oakley (University College London) and colleagues, who compared brain activation of genuinely hypnotized people given suggestions for leg paralysis with brain activation of people simply asked to fake hypnosis and paralysis.
Milton Erickson (1901–1980), the founding president of the American Society for Clinical Hypnosis and a fellow of the American Psychiatric Association, the American Psychological Association, and the American Psychopathological Association, was one of the most influential post-war hypnotherapists. He wrote several books and journal articles on the subject. During the 1960s, Erickson popularized a new branch of hypnotherapy, known as Ericksonian therapy, characterised primarily by indirect suggestion, "metaphor" (actually analogies), confusion techniques, and double binds in place of formal hypnotic inductions. However, the difference between Erickson's methods and traditional hypnotism led contemporaries such as André Weitzenhoffer to question whether he was practising "hypnosis" at all, and his approach remains in question.

In 1784, at the request of King Louis XVI, a Board of Inquiry started to investigate whether animal magnetism existed. Among the board members were founding father of modern chemistry Antoine Lavoisier, Benjamin Franklin, and an expert in pain control, Joseph-Ignace Guillotin. They investigated the practices of a disaffected student of Mesmer, one Charles d'Eslon (1750–1786), and though they concluded that Mesmer's results were valid, their placebo-controlled experiments using d'Eslon's methods convinced them that mesmerism was most likely due to belief and imagination rather than to an invisible energy ("animal magnetism") transmitted from the body of the mesmerist.

As a hypnotherapist, I've seen first-hand the incredible changes that this form of therapy can bring. I once had a client with an intense phobia of maggots who couldn't so much as utter the word without experiencing a strong physical and emotional response. But after just two sessions she found that she was able to talk about them comfortably and was also willing to watch videos of them online without feeling disturbed. She was hardly able to believe her progress.

Although there are different techniques, clinical hypnotherapy is generally performed in a calm, therapeutic environment. The therapist will guide you into a relaxed, focused state and ask you to think about experiences and situations in positive ways that can help you change the way you think and behave. Unlike some dramatic portrayals of hypnosis in movies, books, or on stage, you will not be unconscious, asleep, or in any way out of control of yourself. You will hear the therapist’s suggestions, but it is up to you to decide whether or not to act on them.